Article
Characterization of the Thyroid Cancer Genomic Landscape by Plasma-Based Circulating Tumor DNA Next-Generation Sequencing.
Thyroid : official journal of the American Thyroid Association - 1 Feb 2024
Tarasova Valentina D, Tsai Jill, Masannat Jude, Hernandez Prera Juan C, Hallanger Johnson Julie, Veloski Colleen, Agosto Salgado Sarimar, McIver Bryan, Drusbosky Leylah M, Chung Christine H
Abstract excerpt
Background: The limited availability of targeted therapies in thyroid cancer (TC) has challenged conventional treatment algorithms and has established urgency for the identification of targetable genomic abnormalities. In addition to widely adopted tissue-based next-generation sequencing (NGS), plasma-based circulating tumor DNA (ctDNA) NGS is rapidly emerging as a genomic biomarker detection method and is...
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