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Article

IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice

28 Feb 2023

Abstract excerpt

The establishment of pregnancy depends on interactions between the epithelial and stromal cells of the endometrium that drive the decidual reaction that remodels the stroma and enables embryo implantation. Decidualization in mice also depends on ovarian hormones and the presence of a blastocyst. Hedgehog signaling is transduced by primary cilia in many tissues and is involved in epithelial-stromal cross-talk...

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PMID: 36853961
DOI: 10.1126/scisignal.add0645

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