Article
Primer and interviews: Diverse connections between primary cilia and Hedgehog signaling.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Apr 2010
Kiefer Julie C
Abstract excerpt
On the surface, the Hedgehog (Hh) pathway and primary cilia make strange bedfellows. Hh is a dynamic regulator of a myriad of developmental processes, ranging from spinal cord and limb patterning to lung branching morphogenesis. By contrast, immotile primary cilia were long considered ancestral holdovers with no known function. Considering the disparate perceptions of these two phenomena, the relatively recent...
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