Article
Characterization of the IGF2 Imprinted Gene Methylation Status in Bovine Oocytes during Folliculogenesis.
PloS one - 1 Jan 2015
Mendonça Anelise dos Santos, Guimarães Ana Luíza Silva, da Silva Naiara Milagres Augusto, Caetano Alexandre Rodrigues, Dode Margot Alves Nunes, Franco Maurício Machaim
Abstract excerpt
DNA methylation reprogramming occurs during mammalian gametogenesis and embryogenesis. Sex-specific DNA methylation patterns at specific CpG islands controlling imprinted genes are acquired during this window of development. Characterization of the DNA methylation dynamics of imprinted genes acquired by oocytes during folliculogenesis is essential for understanding the physiological and genetic aspects of female...
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