Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Viral Population Heterogeneity and Fluctuating Mutational Pattern during a Persistent SARS-CoV-2 Infection in an Immunocompromised Patient.

Viruses - 19 Jan 2023

Brandolini Martina, Zannoli Silvia, Gatti Giulia, Arfilli Valentina, Cricca Monica, Dirani Giorgio, Denicolò Agnese, Semprini Simona, Grumiro Laura, Imola Manuela, Larne Damiano, Marino Maria Michela, Manera Martina, Mancini Andrea, Taddei Francesca, Zagarrigo Manuel, Biagetti Carlo, Sambri Vittorio

Abstract excerpt

Literature offers plenty of cases of immunocompromised patients, who develop chronic and severe SARS-CoV-2 infections. The aim of this study is to provide further insight into SARS-CoV-2 evolutionary dynamic taking into exam a subject suffering from follicular lymphoma, who developed a persistent infection for over 7 months. Eight nasopharyngeal swabs were obtained, and were analyses by qRT-PCR for diagnostic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19
Share to Immunocompromised Host

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 36851504
DOI: 10.3390/v15020291
PMCID: PMC9962589

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Viral Population Heterogeneity and Fluctuating Mutational Pattern during a Persistent SARS-CoV-2 Infection in an Immunocompromised Patient.PMID 36851504Read ↗

Long-Term Evolution of SARS-CoV-2 in an Immunocompromised Patient with Non-Hodgkin Lymphoma.Semantic proximity Read ↗

Different Within-Host Viral Evolution Dynamics in Severely Immunosuppressed Cases with Persistent SARS-CoV-2Semantic proximity Read ↗

SARS-CoV-2 shedding, infectivity and evolution in an immunocompromised adult patientSemantic proximity Read ↗

Molecular Characterization of Persistent SARS-CoV-2 Infections in Immunocompromised Patients.Semantic proximity Read ↗

Case reports of persistent SARS-CoV-2 infection outline within-host viral evolution in immunocompromised patients.Semantic proximity Read ↗

The longest persistence of viable SARS-CoV-2 with recurrence of viremia and relapsing symptomatic COVID-19 in an immunocompromised patient – a case studySemantic proximity Read ↗

SARS-CoV-2 population dynamics in immunocompetent individuals in a closed transmission chain shows genomic diversity over the course of infection.Semantic proximity Read ↗

Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host.Semantic proximity Read ↗

SARS-CoV-2 escape from cytotoxic T cells during long-term COVID-19Semantic proximity Read ↗

Persistent SARS-CoV-2 infection and increasing viral variants in children and young adults with impaired humoral immunitySemantic proximity Read ↗

Extensive Intra-host evolution and T cell escape by SARS-CoV-2 in a 2.5-year persistent infection of an immunocompromised hostSemantic proximity Read ↗

Long-Term Intra-Host Evolution of SARS-CoV-2 in an Immunocompromised Patient: Recombination and Within-Host Mutations Driving Viral AdaptationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.