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Article

Mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system: A mini-review.

World journal of gastroenterology - 21 May 2022

Toor Deepak, Loree Jonathan M, Gao Zu-Hua, Wang Gang, Zhou Chen

Abstract excerpt

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are rare mixed tumors containing both neuroendocrine (NE) and non-NE components. Each component must occupy at least 30% of the tumor volume by definition. Recent molecular evidence suggests MiNENs are clonal neoplasms and potentially harbor targetable mutations similar to conventional carcinomas. There have been multiple changes in the nomenclature and...

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Identifiers

PMID: 35664032
DOI: 10.3748/wjg.v28.i19.2076
PMCID: PMC9134131

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