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Article

Influence of Mutations of Conserved Arginines on Neuropeptide Binding in the DPP III Active Site.

Molecules (Basel, Switzerland) - 19 Feb 2023

Tomić Antonija, Karačić Zrinka, Tomić Sanja

Abstract excerpt

Dipeptidyl peptidase III (DPP III), a zinc exopeptidase, is involved in the final steps of intercellular protein degradation and has a marked affinity for opioid peptides such as enkephalins and endomorphins. Recently, we characterized a number of neuropeptides as potential substrates and inhibitors of human DPP III and provided an explanation for their differential behavior. These studies prompted us to...

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PMID: 36838964
DOI: 10.3390/molecules28041976
PMCID: PMC9967118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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