Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coinfection of Dermal Fibroblasts by Human Cytomegalovirus and Human Herpesvirus 6 Can Boost the Expression of Fibrosis-Associated MicroRNAs

6 Feb 2023

Abstract excerpt

Tissue fibrosis can affect every type of tissue or organ, often leading to organ malfunction; however, the mechanisms involved in this process are not yet clarified. A role has been hypothesized for Human Cytomegalovirus (HCMV) and Human Herpesvirus 6 (HHV-6) infections as triggers of systemic sclerosis (SSc), a severe autoimmune disease causing progressive tissue fibrosis, since both viruses and antiviral immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hair Growth and Disorders
Share to Inflammatory Myopathies and Dermatomyositis
Share to Systemic Sclerosis and Related Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36838377
DOI: 10.3390/microorganisms11020412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coinfection of Dermal Fibroblasts by Human Cytomegalovirus and Human Herpesvirus 6 Can Boost the Expression of Fibrosis-Associated MicroRNAsPMID 36838377Read ↗

Human Cytomegalovirus and Human Herpesvirus 6 Coinfection of Dermal Fibroblasts Enhances the Pro-Inflammatory Pathway Predisposing to Fibrosis: The Possible Impact on Systemic SclerosisSemantic proximity Read ↗

Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma.Semantic proximity Read ↗

Human cytomegalovirus blocks canonical TGFβ signaling during lytic infection to limit induction of type I interferonsSemantic proximity Read ↗

Induction of type I and III interferons by viral and endogenous stimuli in systemic sclerosisSemantic proximity Read ↗

Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell typesSemantic proximity Read ↗

Tissue specific signature of HHV-6 infection in ME/CFSSemantic proximity Read ↗

Coinfection of Human Herpesviruses 6A (HHV-6A) and HHV-6B as Demonstrated by Novel Digital Droplet PCR AssaySemantic proximity Read ↗

Autocrine overexpression of CTGF maintains fibrosis: RDA analysis of fibrosis genes in systemic sclerosis.Semantic proximity Read ↗

Reactivation of human cytomegalovirus inhibits expression of liver fibrosis related cytokines in patients chronically infected with hepatitis C virus genotype 4a.Semantic proximity Read ↗

The immunoregulatory effects of CMV-infection in human fibroblasts and the impact on cellular senescenceSemantic proximity Read ↗

Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblastsSemantic proximity Read ↗

Human Herpesvirus 6A Is a Risk Factor for Multiple SclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.