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Article

The immunoregulatory effects of CMV-infection in human fibroblasts and the impact on cellular senescence

29 Mar 2012

Abstract excerpt

BACKGROUND: As a chronic antigenic stressor human Cytomegalovirus (CMV) contributes substantially to age-related alterations of the immune system. Even though monocytes have the greatest propensity for CMV-infection and seem to be an important host for the virus during latency, fibroblasts are also discussed to be target cells of CMV in vivo. However, little is known so far about general immunoregulatory...

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Share to Cytomegalovirus and herpesvirus research
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PMID: 22455503
DOI: 10.1186/1742-4933-9-1

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