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Article

Differential Expression of MED12-Associated Coding RNA Transcripts in Uterine Leiomyomas.

International journal of molecular sciences - 13 Feb 2023

Chuang Tsai-Der, Gao Jianjun, Quintanilla Derek, McSwiggin Hayden, Boos Drake, Yan Wei, Khorram Omid

Abstract excerpt

Recent studies have demonstrated that somatic MED12 mutations in exon 2 occur at a frequency of up to 80% and have a functional role in leiomyoma pathogenesis. The objective of this study was to elucidate the expression profile of coding RNA transcripts in leiomyomas, with and without these mutations, and their paired myometrium. Next-generation RNA sequencing (NGS) was used to systematically profile the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36835153
DOI: 10.3390/ijms24043742
PMCID: PMC9960582

Genes

MED12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Differential Expression of MED12-Associated Coding RNA Transcripts in Uterine Leiomyomas.PMID 36835153Read ↗

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