Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gata2a Mutation Causes Progressive Microphthalmia and Blindness in Nile Tilapia.

International journal of molecular sciences - 10 Feb 2023

Liu Xingyong, Zhou Li, Li Wenbo, Wu Jiahong, Wang Deshou

Abstract excerpt

The normal development of lens fiber cells plays a critical role in lens morphogenesis and maintaining transparency. Factors involved in the development of lens fiber cells are largely unknown in vertebrates. In this study, we reported that GATA2 is essential for lens morphogenesis in Nile tilapia (Oreochromis niloticus). In this study, Gata2a was detected in the primary and secondary lens fiber cells, with the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cichlids
Share to Blindness
Share to GATA2 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microphthalmos

Share to Mutation

Share to Tilapia

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 36834978
DOI: 10.3390/ijms24043567
PMCID: PMC9958714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gata2a Mutation Causes Progressive Microphthalmia and Blindness in Nile Tilapia.PMID 36834978Read ↗

Homozygous Mutation of gsdf Causes Infertility in Female Nile Tilapia (Oreochromis niloticus).Semantic proximity Read ↗

A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function.Semantic proximity Read ↗

Physiological impact and comparison of mutant screening methods in piwil2 KO founder Nile tilapia produced by CRISPR/Cas9 system.Semantic proximity Read ↗

Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.Semantic proximity Read ↗

Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber.Semantic proximity Read ↗

A zebrafish model of foxe3 deficiency demonstrates lens and eye defects with dysregulation of key genes involved in cataract formation in humans.Semantic proximity Read ↗

Transcription factors underlying photoreceptor diversitySemantic proximity Read ↗

Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators.Semantic proximity Read ↗

Teleost lens development and degeneration.Semantic proximity Read ↗

The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2.Semantic proximity Read ↗

Modeling ocular lens disease in XenopusSemantic proximity Read ↗

Transcription factor GATA‐3 is essential for lens developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.