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Tyk2 Targeting in Immune-Mediated Inflammatory Diseases

8 Feb 2023

Abstract excerpt

The Janus kinase (Jak)/signal transducer and activating protein (STAT) pathways mediate the intracellular signaling of cytokines in a wide spectrum of cellular processes. They participate in physiologic and inflammatory cascades and have become a major focus of research, yielding novel therapies for immune-mediated inflammatory diseases (IMID). Genetic linkage has related dysfunction of Tyrosine kinase 2...

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PMID: 36834806
DOI: 10.3390/ijms24043391

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