Article
Heterogenous Differences in Cellular Senescent Phenotypes in Pre-Eclampsia and IUGR following Quantitative Assessment of Multiple Biomarkers of Senescence.
International journal of molecular sciences - 4 Feb 2023
Manna Samprikta, Mc Elwain Colm J, Maher Gillian M, Giralt Martín Marta, Musumeci Andrea, McCarthy Fergus P, McCarthy Cathal
Abstract excerpt
Premature ageing of the placenta in pregnancy outcomes is associated with the persistent presence of oxidative stress and placental insufficiency reducing its functional capacity. In this study, we investigated cellular senescence phenotypes of pre-eclampsia and IUGR pregnancies by simultaneously measuring several biomarkers of senescence. Maternal plasma and placental samples were collected at term gestation...
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