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Placentas From SARS‐CoV‐2 Infection During Pregnancy Exhibit Foci of Oxidative Stress and DNA Damage

30 Dec 2024

Abstract excerpt

PROBLEM: COVID-19 during pregnancy is linked to increased maternal morbidity and a higher incidence of preterm births (PTBs), yet the underlying mechanisms remain unclear. Cellular senescence, characterized by the irreversible cessation of cell division, is a critical process in placental function, and its dysregulation has been implicated in pregnancy complications like PTB. Senescence can be induced by various...

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PMID: 39739931
DOI: 10.1111/aji.70034

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