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Article

Cellular senescence-related gene variants as risk factors for recurrent pregnancy loss.

Molecular biology reports - 28 Jul 2026

Nabinger Eduarda, Pretto Luiza, Cremonese Filippi-Chiela Eduardo, Woycinck Kowalski Thayne, Vieira Sanseverino Maria Teresa, Sales Luiz Vianna Fernanda, Rosa Fraga Lucas

Abstract excerpt

BACKGROUND: Recurrent pregnancy loss (RPL) is characterized by two or more pregnancy losses. Despite its etiology encompassing known risk factors, over half of the cases remain idiopathic. In this sense, the search for molecular and cellular mechanisms that could be related to this condition is essential for explaining, at least in part, these cases. Cellular senescence (CS) is a state of cell cycle arrest that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42517973
DOI: 10.1007/s11033-026-12281-0
PMCID: PMC13415376

Genes

CS
CDKN1A
AKT1
CDKN2A
EP300
IFNG
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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