Article
The genetic and evolutionary basis of gene expression variation in East Africans.
Genome biology - 24 Feb 2023
Kelly Derek E, Ramdas Shweta, Ma Rong, Rawlings-Goss Renata A, Grant Gregory R, Ranciaro Alessia, Hirbo Jibril B, Beggs William, Yeager Meredith, Chanock Stephen, Nyambo Thomas B, Omar Sabah A, Woldemeskel Dawit, Belay Gurja, Li Hongzhe, Brown Christopher D, Tishkoff Sarah A
Abstract excerpt
BACKGROUND: Mapping of quantitative trait loci (QTL) associated with molecular phenotypes is a powerful approach for identifying the genes and molecular mechanisms underlying human traits and diseases, though most studies have focused on individuals of European descent. While important progress has been made to study a greater diversity of human populations, many groups remain unstudied, particularly among...
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