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Article

Comparative Genomic Profiling of Second Breast Cancers following First Ipsilateral Hormone Receptor-Positive Breast Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2023

Rassy Elie, Garberis Ingrid, Tran-Dien Alicia, Job Bastien, Chung-Scott Véronique, Bouakka Ibrahim, Bassil Josiane, Ferkh Rachel, Lacroix-Triki Magali, Zanconati Fabrizio, Giudici Fabiola, Generali Daniele, Rouleau Etienne, Lacroix Ludovic, Andre Fabrice, Pistilli Barbara

Abstract excerpt

PURPOSE: We compared the mutational profile of second breast cancers (SBC) following first ipislateral hormone receptor-positive breast cancers of patient-matched tumors to distinguish new primaries from true recurrences. EXPERIMENTAL DESIGN: Targeted next-generation sequencing using the Oncomine Tumor Mutation Load Assay. Variants were filtered according to their allele frequency ≥ 5%, read count ≥ 5X, and...

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PMID: 36805183
DOI: 10.1158/1078-0432.CCR-22-2883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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