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Article

IL-6, IL-1β and TNF-α regulation of the chondrocyte phenotype: a possible mechanism of haemophilic cartilage destruction.

Hematology (Amsterdam, Netherlands) - 1 Dec 2023

Zheng Liujie, Han Zhiwei, Luo Dasheng, Li Jiale, Pang Nanyu, Ding Mingyang, Ye Houlong, Zhu Keyan, Yao Yunfeng

Abstract excerpt

OBJECTIVE: Proinflammatory cytokines are considered to be one of the key causes of haemophilic cartilage destruction by inducing chondrocyte apoptosis and extracellular matrix degradation. However, few studies have focused on how proinflammatory cytokines regulate the phenotypic changes of chondrocytes, which may be an important factor in haemophilic cartilage degradation pathogenesis. More understanding is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36799502
DOI: 10.1080/16078454.2023.2179867

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