Clinical utility of genomic profiling of AML using paraffin-embedded bone marrow clots: HM-SCREEN-Japan 01.

doi:10.1111/cas.15746

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Clinical utility of genomic profiling of AML using paraffin-embedded bone marrow clots: HM-SCREEN-Japan 01.

Cancer science - 1 May 2023

Hosono Naoko, Chi SungGi, Yamauchi Takahiro, Fukushima Kentaro, Shibayama Hirohiko, Katagiri Seiichiro, Gotoh Akihiko, Eguchi Motoki, Morishita Takanobu, Ogasawara Reiki, Kondo Takeshi, Yanada Masamitsu, Yamamoto Kazuhito, Kobayashi Tsutomu, Kuroda Junya, Usuki Kensuke, Utsu Yoshikazu, Yoshimitsu Makoto, Ishitsuka Kenji, Ono Takaaki, Takahashi Naoto, Iyama Satoshi, Kojima Kensuke, Nakamura Yukinori, Fukuhara Suguru, Izutsu Koji, Abutani Hikaru, Yamauchi Nobuhiko, Yuda Junichiro, Minami Yosuke

Abstract excerpt

Next-generation sequencing of AML has identified specific genetic mutations in AML patients. Hematologic Malignancies (HM)-SCREEN-Japan 01 is a multicenter study to detect actionable mutations using paraffin-embedded bone marrow (BM) clot specimens rather than BM fluid in AML patients for whom standard treatment has not been established. The purpose of this study is to evaluate the presence of potentially...

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PMID: 36793248
DOI: 10.1111/cas.15746
PMCID: PMC10154825

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