Article
Gene expression profiling of acute myeloid leukemia samples from adult patients with AML-M1 and -M2 through boutique microarrays, real-time PCR and droplet digital PCR.
International journal of oncology - 1 Mar 2018
Handschuh Luiza, Kaźmierczak Maciej, Milewski Marek C, Góralski Michał, Łuczak Magdalena, Wojtaszewska Marzena, Uszczyńska-Ratajczak Barbara, Lewandowski Krzysztof, Komarnicki Mieczysław, Figlerowicz Marek
Abstract excerpt
Acute myeloid leukemia (AML) is the most common and severe form of acute leukemia diagnosed in adults. Owing to its heterogeneity, AML is divided into classes associated with different treatment outcomes and specific gene expression profiles. Based on previous studies on AML, in this study, we designed and generated an AML-array containing 900 oligonucleotide probes complementary to human genes implicated in...
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