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Article

Circulating macrophage colony-stimulating factor levels and stroke: A Mendelian randomization study.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Apr 2023

Cao Liping, Liu Dandan, Karhunen Ville, Ren Yi, Ye Dan, Gao Jie, Gill Dipender, Wang Mengmeng

Abstract excerpt

OBJECTIVES: Colony-stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor, has been shown to be associated with risk of ischemic stroke in conventional epidemiological study. We performed a Mendelian randomization analysis to evaluate the effects of genetically predicted circulating CSF1 levels on stroke and carotid intima-media thickness (cIMT). METHODS: Genetic variants robustly...

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Carotid Intima-Media Thickness
Cerebral Hemorrhage
Genome-Wide Association Study
Ischemic Stroke
Macrophage Colony-Stimulating Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

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PMID: 36780760
DOI: 10.1016/j.jstrokecerebrovasdis.2023.107050

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