Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of O-Antigen Chain Length Regulation on the Immunogenicity of Shigella and Salmonella Generalized Modules for Membrane Antigens (GMMA).

International journal of molecular sciences - 28 Jan 2021

Gasperini Gianmarco, Raso Maria Michelina, Arato Vanessa, Aruta Maria Grazia, Cescutti Paola, Necchi Francesca, Micoli Francesca

Abstract excerpt

Recently, generalized modules for membrane antigens (GMMA) technology has been proposed as an alternative approach to traditional glycoconjugate vaccines for O-antigen delivery. Saccharide length is a well-known parameter that can impact the immune response induced by glycoconjugates both in terms of magnitude and quality. However, the criticality of O-antigen length on the immune response induced by GMMA-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Bacterial
Share to Bacterial Vaccines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Design

Share to Immunization

Share to O Antigens

Share to Shigella flexneri

Share to Shigella sonnei

Source

Open in PubMed Open full text

Identifiers

PMID: 33525644
DOI: 10.3390/ijms22031309
PMCID: PMC7865430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of O-Antigen Chain Length Regulation on the Immunogenicity of Shigella and Salmonella Generalized Modules for Membrane Antigens (GMMA).PMID 33525644Read ↗

Characterization of O-antigen delivered by Generalized Modules for Membrane Antigens (GMMA) vaccine candidates against nontyphoidal Salmonella.Semantic proximity Read ↗

Exploring the Role of GMMA Components in the Immunogenicity of a 4-Valent Vaccine against ShigellaSemantic proximity Read ↗

GMMA-Based Vaccines: The Known and The UnknownSemantic proximity Read ↗

Towards a Four-Component GMMA-Based Vaccine against ShigellaSemantic proximity Read ↗

Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal SalmonellaSemantic proximity Read ↗

Combined effects of glycan chain length and linkage type on the immunogenicity of glycoconjugate vaccinesSemantic proximity Read ↗

Modulation of endotoxicity of Shigella generalized modules for membrane antigens (GMMA) by genetic lipid A modifications: relative activation of TLR4 and TLR2 pathways in different mutants.Semantic proximity Read ↗

Recent Advances in the Synthesis of Glycoconjugates for Vaccine DevelopmentSemantic proximity Read ↗

Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to ShigellaSemantic proximity Read ↗

The Shigella Vaccines PipelineSemantic proximity Read ↗

Towards establishing correlates of protection against shigellosis: assessing immunological endpoints across immune responses to the Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) candidate vaccine (1790GAHB).Semantic proximity Read ↗

Targeted lipid A modification of <i>Shigella</i> vaccine strains reduced endotoxicity without compromising immunogenicity or invasivenessSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.