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Towards establishing correlates of protection against shigellosis: assessing immunological endpoints across immune responses to the Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) candidate vaccine (1790GAHB).

2023-09-21

Abstract excerpt

<title>Abstract</title> <p><italic>Shigella</italic> spp. are a leading bacterial cause of diarrhea. No widely licensed vaccines are available and there is no generally accepted correlate of protection. We tested a <italic>S. sonnei</italic> Generalized Modules for Membrane Antigen (GMMA)-based vaccine (1790GAHB) in a phase 2b, placebo-controlled, randomized, controlled human infection model study (NCT03527173) e...

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Literature Corpus work
bd9df88e-df86-502b-946c-8b0eadaf3589
DOI
10.21203/rs.3.rs-3314985/v1
Open publication

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Towards establishing correlates of protection against shigellosis: assessing immunological endpoints across immune responses to the Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) candidate vaccine (1790GAHB).DOI 10.21203/rs.3.rs-3314985/v1
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