Comprehensive analysis of histone acetylation‐related genes in glioblastoma and lower‐grade gliomas: Insights into drug sensitivity, molecular subtypes, immune infiltration, and prognosis

Abstract excerpt

OBJECTIVES: The purpose of this research was to study the impact of histone acetylation on glioblastoma multiforme (GBM) and lower-grade gliomas (LGG) and its potential implications for patient prognosis. We aimed to assess the histone acetylation score (HAs) and its relationship with key genes involved in histone acetylation regulation. METHOD: The TCGA-GBMLGG dataset, which provides comprehensive genomic and...

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• Ferroptosis and cancer prognosis
• Glioma Diagnosis and Treatment
• Histone Deacetylase Inhibitors Research