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Efficient production of recombinant human adiponectin in egg white using genome edited chickens

24 Jan 2023

Abstract excerpt

The prevalence of obesity-related metabolic diseases caused by insulin resistance is rapidly increasing worldwide. Adiponectin (ADPN), a hormone derived from adipose tissue, is a potential therapeutic agent for insulin resistance. Chickens are considered efficient bioreactors for recombinant protein production because they secrete large amounts of high-concentration proteins from the oviduct. Additionally,...

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PMID: 36761986
DOI: 10.3389/fnut.2022.1068558

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