Article
RNA-Seq Analysis of Abdominal Fat in Genetically Fat and Lean Chickens Highlights a Divergence in Expression of Genes Controlling Adiposity, Hemostasis, and Lipid Metabolism.
PloS one - 1 Jan 2015
Resnyk Christopher W, Chen Chuming, Huang Hongzhan, Wu Cathy H, Simon Jean, Le Bihan-Duval Elisabeth, Duclos Michel J, Cogburn Larry A
Abstract excerpt
Genetic selection for enhanced growth rate in meat-type chickens (Gallus domesticus) is usually accompanied by excessive adiposity, which has negative impacts on both feed efficiency and carcass quality. Enhanced visceral fatness and several unique features of avian metabolism (i.e., fasting hyperglycemia and insulin insensitivity) mimic overt symptoms of obesity and related metabolic disorders in humans....
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