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Article

Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2.

Journal of structural and functional genomics - 1 Mar 2015

Tanabe Hiroaki, Motoyama Kanna, Ikeda Mariko, Wakiyama Motoaki, Terada Takaho, Ohsawa Noboru, Hosaka Toshiaki, Hato Masakatsu, Fujii Yoshifumi, Nakamura Yoshihiro, Ogasawara Satoshi, Hino Tomoya, Murata Takeshi, Iwata So, Okada-Iwabu Miki, Iwabu Masato, Hirata Kunio, Kawano Yoshiaki, Yamamoto Masaki, Kimura-Someya Tomomi, Shirouzu Mikako, Yamauchi Toshimasa, Kadowaki Takashi, Yokoyama Shigeyuki

Abstract excerpt

The adiponectin receptors (AdipoR1 and AdipoR2) are membrane proteins with seven transmembrane helices. These receptors regulate glucose and fatty acid metabolism, thereby ameliorating type 2 diabetes. The full-length human AdipoR1 and a series of N-terminally truncated mutants of human AdipoR1 a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25575462
DOI: 10.1007/s10969-014-9192-z
PMCID: PMC4329188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25575462-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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