Article
Two distinct pathogenic pathways of digital papillary adenocarcinoma - BRAF mutation or low-risk HPV infection.
Journal of cutaneous pathology - 1 Jun 2023
Bui Chau M, Pukhalskaya Tatsiana, Smoller Bruce R, Zengin Hatice Betul, Heneidi Saleh, Vail Eric, Makhoul Elias, Balzer Bonnie
Abstract excerpt
Digital papillary adenocarcinoma (DPA) is a rare neoplasm that can exhibit local recurrence and distant metastasis. We present a series of eight cases of DPA showing two distinct clinical presentations, morphologies, immunophenotypes, and molecular features. Four cases were characterized by painless, slow-growing nodules located on the digits. The lesions were small, well-defined, and confined in the dermis....
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