Article
Low-grade papillary Schneiderian carcinoma with TP53 mutation: a case report and review of the literature.
Diagnostic pathology - 11 Apr 2023
Yuzawa Sayaka, Michizuka Tomohiko, Kakisaka Rika, Ono Yusuke, Hayashi Manami, Takahara Miki, Katada Akihiro, Mizukami Yusuke, Tanino Mishie
Abstract excerpt
BACKGROUND: Low-grade papillary Schneiderian carcinoma (LGPSC) is a relatively new entity of the sinonasal tract and is characterized by a bland morphology simulating sinonasal papilloma, invasive growth pattern with pushing borders, and aggressive clinical behavior with multiple recurrences and metastatic potential. Recently, DEK::AFF2 fusions were identified in LGPSC. However, some LPGSCs lack DEK::AFF2 fusion,...
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