Article
TG-interacting factor 1 improves risk stratification in patients with NPM1-mutated acute myeloid leukemia.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jul 2023
Tang Hongwei, Zhang Nan, Li Huan, Chen Ying, Liu Xinlei, Xiao Hongbo, Deng Jianchuan, Zhou Kang
Abstract excerpt
BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease characterized by diverse genetic abnormalities. The NPM1 is the most commonly mutated gene in newly diagnosed patients. Optimizing risk stratification in this population could facilitate more rational clinical decision-making. OBJECTIVES: To identify biomarkers that optimize risk stratification in AML patients with NPM1 mutations. MATERIAL AND...
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