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Validation of a breast cancer risk prediction model based on the key risk factors: family history, mammographic density and polygenic risk

7 Feb 2023

Abstract excerpt

PURPOSE: We compared a simple breast cancer risk prediction model, BRISK (which includes mammographic density, polygenic risk and clinical factors), against a similar model with more risk factors (simplified Rosner) and against two commonly used clinical models (Gail and IBIS). METHODS: Using nested case-control data from the Nurses' Health Study, we compared the models' association, discrimination and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36749458
DOI: 10.1007/s10549-022-06834-7

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