Article
Breast Cancer Risk Model Requirements for Counseling, Prevention, and Screening.
Journal of the National Cancer Institute - 1 Sept 2018
Gail Mitchell H, Pfeiffer Ruth M
Abstract excerpt
Background: Incorporation of polygenic risk scores and mammographic density into models to predict breast cancer incidence can increase discriminatory accuracy (area under the receiver operating characteristic curve [AUC]) from 0.6 for models based only on epidemiologic factors to 0.7. It is timely to assess what impact these improvements will have on individual counseling and on public health prevention and...
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