Article
Shared genetics of psychiatric disorders and type 2 diabetes:a large-scale genome-wide cross-trait analysis.
Journal of psychiatric research - 1 Mar 2023
Ding Hui, Xie Minyao, Wang Jinyi, Ouyang Mengyuan, Huang Yanyuan, Yuan Fangzheng, Jia Yunhan, Zhang Xuedi, Liu Na, Zhang Ning
Abstract excerpt
BACKGROUND: Individuals with psychiatric disorders have elevated rates of type 2 diabetes comorbidity. Although little is known about the shared genetics and causality of this association. Thus, we aimed to investigate shared genetics and causal link between different type 2 diabetes and psychiatric disorders. METHODS: We conducted a large-scale genome-wide cross-trait association study(GWAS) to investigate...
Topics
- Humans
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Autism Spectrum Disorder
- Bipolar Disorder
- Attention Deficit Disorder with Hyperactivity
- Genome-Wide Association Study
- Genetic Predisposition to Disease
- Polymorphism, Single Nucleotide
- Alpha-Ketoglutarate-Dependent Dioxygenase FTO