Article
Genetic association study between the detected risk variants based upon type II diabetes GWAS and psychotic disorders in the Japanese population.
Journal of human genetics - 1 Jan 2014
Kajio Yusuke, Kondo Kenji, Saito Takeo, Iwayama Yoshimi, Aleksic Branko, Yamada Kazuo, Toyota Tomoko, Hattori Eiji, Ujike Hiroshi, Inada Toshiya, Kunugi Hiroshi, Kato Tadafumi, Yoshikawa Takeo, Ozaki Norio, Ikeda Masashi, Iwata Nakao
Abstract excerpt
Several epidemiological and genetic studies have suggested that the risk of type II diabetes (T2D) is likely to overlap with the susceptibility to psychotic disorders such as schizophrenia (SCZ) and bipolar disorder (BD). In this study, we aimed to examine the association of single-nucleotide polymorphisms (SNPs) detected in previous T2D genome-wide association studies (GWAS) with SCZ, BD and psychosis (SCZ plus...
Topics
- Alleles
- Asian People
- Carrier Proteins
- Diabetes Mellitus, Type 2
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Hepatocyte Nuclear Factor 4
- High Mobility Group Proteins