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Article

Pancreatitis polygenic risk score is independently associated with all-cause acute pancreatitis risk in the UK Biobank.

Journal of gastroenterology and hepatology - 1 Dec 2024

Guay Simon-Pierre, Gagnon Eloi, Paquette Martine, Thériault Sébastien, Arsenault Benoit J, Baass Alexis

Abstract excerpt

BACKGROUND AND AIM: Acute pancreatitis (AP) is a complex disease most commonly caused by gallstones, alcohol intake, or hypertriglyceridemia. Even in subjects with hypertriglyceridemia, the risk of AP is heterogeneous. Identifying individuals with a high genetic susceptibility to AP could contribute to a better risk stratification in the clinic. This study aimed to determine if a weighted polygenic risk score...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39385584
DOI: 10.1111/jgh.16759

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