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Article

Identification of an Activating PDGFRA Deletion in a Novel Sinonasal Soft Tissue Neoplasm.

Head and neck pathology - 1 Jun 2023

Watkins James A, Hatcher Helen, Malhotra Shalini, Amen Furrat, Bruty Jonathan, Trotman Jamie, Tarpey Patrick, Tadross John A

Abstract excerpt

BACKGROUND: Spindle cell tumours in the sinonasal area are diagnostically challenging. We identified a neoplasm that defied histopathological classification using current criteria. METHODS: The case was subjected to histopathological, immunohistochemical and molecular analysis using a large small variant DNA panel. RESULTS: The tumour comprised cytologically bland epithelioid spindle cells with a rich...

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Identifiers

PMID: 36723852
DOI: 10.1007/s12105-023-01526-0
PMCID: PMC10293132

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