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Article

Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model.

Journal of neuroinflammation - 31 Jan 2023

Roseborough A D, Myers S J, Khazaee R, Zhu Y, Zhao L, Iorio E, Elahi F M, Pasternak S H, Whitehead S N

Abstract excerpt

Chronic microglia activation post-stroke is associated with worse neurological and cognitive outcomes. However, measurement of microglia activation in vivo is currently limited. Plasma derived extracellular vesicles (EVs) are cell-specific indicators that may allow for non-invasive measurement of microglia phenotype. The aim of this study was to identify activation-state specific microglia EVs (MEVs) in vitro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36721258
DOI: 10.1186/s12974-023-02708-x
PMCID: PMC9890769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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