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Article

Polymorphisms in ERCC1 C8092A predict progression-free survival in metastatic/recurrent nasopharyngeal carcinoma treated with cisplatin-based chemotherapy.

Cancer chemotherapy and pharmacology - 1 Aug 2013

Chen Cui, Wang Fenghua, Wang Zhiqiang, Li Cong, Luo Huiyan, Liang Ying, An Xin, Shao Jianyong, Li Yuhong

Abstract excerpt

OBJECTIVES: We evaluated whether DNA repair gene polymorphisms had an effect on clinical outcomes in metastatic/recurrent nasopharyngeal carcinoma (NPC) patients treated with cisplatin-based chemotherapy. MATERIALS AND METHODS: Clinical data of 101 patients with metastatic/recurrent NPC between 2004 and 2011 were reviewed. Five potentially functional polymorphisms (ERCC1 Asn118Asn, ERCC1 C8092A, XPD Lys751Gln,...

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Source

Identifiers

PMID: 23712330
DOI: 10.1007/s00280-013-2196-8

Genes

ERCC1
XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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