Article
Calcium-sensing receptor 20 years later.
American journal of physiology. Cell physiology - 1 Aug 2014
Alfadda Tariq I, Saleh Ahmad M A, Houillier Pascal, Geibel John P
Abstract excerpt
The calcium-sensing receptor (CaSR) has played an important role as a target in the treatment of a variety of disease states over the past 20 plus years. In this review, we give an overview of the receptor at the cellular level and then provide details as to how this receptor has been targeted to modulate cellular ion transport mechanisms. As a member of the G protein-coupled receptor (GPCR) family, it has a high...
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