Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monitoring Calcium-Sensing Receptor (CaSR)-Induced Intracellular Calcium Flux Using an Indo-1 Flow Cytometry Assay.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025

Gorvin Caroline M, Howles Sarah A

Abstract excerpt

The calcium-sensing receptor (CaSR) has a critical role in maintaining serum calcium concentrations within the normal physiological range, and mutations in the receptor, or components of its signaling and trafficking pathway, cause disorders of calcium homeostasis. Inactivating mutations cause neonatal severe hyperparathyroidism or familial hypocalciuric hypercalcemia (FHH), while gain-of-function mutations cause...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Calcium Signaling
Share to Flow Cytometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HEK293 Cells

Share to Mutation

Share to Receptors, Calcium-Sensing

Source

Identifiers

PMID: 39395096
DOI: 10.1007/978-1-0716-4164-4_4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monitoring Calcium-Sensing Receptor (CaSR)-Induced Intracellular Calcium Flux Using an Indo-1 Flow Cytometry Assay.PMID 39395096Read ↗

Calcium-sensing receptor (CaSR) mutations and disorders of calcium, electrolyte and water metabolism.Semantic proximity Read ↗

Molecular and clinical insights from studies of calcium-sensing receptor mutationsSemantic proximity Read ↗

A Ca(2+)-sensing receptor: from physiology to inherited disorders of calcium homeostasis.Semantic proximity Read ↗

The calcium-sensing receptor and related diseases.Semantic proximity Read ↗

Rare diseases caused by abnormal calcium sensing and signalling.Semantic proximity Read ↗

[Calcium sensing receptor: physiology and pathology].Semantic proximity Read ↗

Recent advances in calcium-sensing receptor structures and signaling pathways.Semantic proximity Read ↗

Functional Analysis of Calcium-Sensing Receptor Variants Identified in Families Provisionally Diagnosed with Familial Hypocalciuric Hypercalcaemia.Semantic proximity Read ↗

Identification and Functional Characterization of a Calcium-Sensing Receptor Mutation in an Infant with Familial Hypocalciuric Hypercalcemia.Semantic proximity Read ↗

Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.Semantic proximity Read ↗

The role of the calcium-sensing receptor in human disease.Semantic proximity Read ↗

[Extracellular calcium sensing under normal and pathological conditions].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.