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Article

Causal Effects of Kidney Function and Chronic Kidney Disease on Alzheimer's Disease by Analyzing Large-Scale Genome-Wide Association Study Datasets.

Journal of Alzheimer's disease : JAD - 1 Nov 2024

Zhao Hainan, Yuan Hongxia, Wang Ermin

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is the leading cause of dementia. Genetic components play an important role in AD and have been widely evaluated by genome-wide association studies (GWAS) and exome sequencing, and some common and rare genetic variants have been identified. In addition to genetic factors, environment factors have a role in AD. Growing evidence from observational studies linked impaired kidney...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39213079
DOI: 10.3233/JAD-240807

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