Article
Impact of the cyclin D1 A870G polymorphism on susceptibility to sporadic colorectal cancer in Taiwan.
Diseases of the colon and rectum - 1 May 2006
Huang Wen-Shih, Tang Reiping, Lin Paul Y, Changchien Chung Rong, Chen Jinn-Shiun, Chiang Jy-Ming, Yeh Chien-Yuh, Wang Jeng-Yi, Hsieh Ling-Ling
Abstract excerpt
PURPOSE: Cyclin D1 is a regulatory protein involved in the cell cycle of both normal and neoplastic cells. Polymorphism of this gene at codon 242 in exon 4 has impacts on risk of the early-age onset in several malignant neoplasms, including colorectal cancer. This investigation was designed to evaluate the effect of cyclin D1 gene polymorphism on the risk of colorectal cancer in Chinese migrants of the Taiwanese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
