Article
Roles of G protein-coupled receptors in inflammatory bowel disease.
World journal of gastroenterology - 28 Mar 2020
Zeng Zhen, Mukherjee Arjudeb, Varghese Adwin Pidiyath, Yang Xiao-Li, Chen Sha, Zhang Hu
Abstract excerpt
Inflammatory bowel disease (IBD) is a complex disease with multiple pathogenic factors. Although the pathogenesis of IBD is still unclear, a current hypothesis suggests that genetic susceptibility, environmental factors, a dysfunctional immune system, the microbiome, and the interactions of these factors substantially contribute to the occurrence and development of IBD. Although existing and emerging drugs have...
Topics
- Female
- Genetic Predisposition to Disease
- Humans
- Immune System Phenomena
- Inflammatory Bowel Diseases
- Male
- Receptors, Cannabinoid
- Receptors, G-Protein-Coupled
- Signal Transduction