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Article

RHO GTPases: from new partners to complex immune syndromes.

Nature reviews. Immunology - 1 Aug 2021

El Masri Rana, Delon Jérôme

Abstract excerpt

Ras homology (RHO) GTPases are signalling proteins that have crucial roles in triggering multiple immune functions. Through their interactions with a broad range of effectors and kinases, they regulate cytoskeletal dynamics, cell polarity and the trafficking and proliferation of immune cells. The activity and localization of RHO GTPases are highly controlled by classical families of regulators that share...

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Identifiers

PMID: 33547421
DOI: 10.1038/s41577-021-00500-7

Genes

RHO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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