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Article

Comparing the adult and pre‐pubertal testis: Metabolic transitions and the change in the spermatogonial stem cell metabolic microenvironment

23 Jan 2023

Abstract excerpt

BACKGROUND: Survivors of childhood cancer often suffer from infertility. While sperm cryopreservation is not feasible before puberty, the patient's own spermatogonial stem cells could serve as a germ cell reservoir, enabling these patients to father their own children in adulthood through the isolation, in vitro expansion, and subsequent transplantation of spermatogonial stem cells. However, this approach...

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PMID: 36690000
DOI: 10.1111/andr.13397

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