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Multiomics approach to profiling Sertoli cell maturation during development of the spermatogonial stem cell niche

21 Jan 2023

Abstract excerpt

Spermatogonial stem cells (SSCs) are the basis of spermatogenesis, a complex process supported by a specialized microenvironment, called the SSC niche. Postnatal development of SSCs is characterized by distinct metabolic transitions from prepubertal to adult stages. An understanding of the niche factors that regulate these maturational events is critical for the clinical application of SSCs in fertility...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 36688722
DOI: 10.1093/molehr/gaad004

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