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Article

Unique metabolic phenotype and its transition during maturation of juvenile male germ cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2021

Voigt Anna Laura, Kondro Douglas Andrew, Powell Diana, Valli-Pulaski Hanna, Ungrin Mark, Stukenborg Jan-Bernd, Klein Claudia, Lewis Ian A, Orwig Kyle E, Dobrinski Ina

Abstract excerpt

Human male reproductive development has a prolonged prepubertal period characterized by juvenile quiescence of germ cells with immature spermatogonial stem cell (SSC) precursors (gonocytes) present in the testis for an extended period of time. The metabolism of gonocytes is not defined. We demonstrate with mitochondrial ultrastructure studies via TEM and IHC and metabolic flux studies with UHPLC-MS that a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33811704
DOI: 10.1096/fj.202002799R
PMCID: PMC8212869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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