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Article

Biogenesis of JC polyomavirus associated extracellular vesicles

1 May 2022

Abstract excerpt

JC polyomavirus (JCPyV) is a small, non-enveloped virus that persists in the kidney in about half the adult population. In severely immune-compromised individuals JCPyV causes the neurodegenerative disease progressive multifocal leukoencephalopathy (PML) in the brain. JCPyV has been shown to infect cells by both direct and indirect mechanisms, the latter involving extracellular vesicle (EV) mediated infection....

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PMID: 36688929
DOI: 10.1002/jex2.43

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