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The Human Polyoma JC Virus Agnoprotein Acts as a Viroporin

11 Mar 2010

Abstract excerpt

Virus infections can result in a range of cellular injuries and commonly this involves both the plasma and intracellular membranes, resulting in enhanced permeability. Viroporins are a group of proteins that interact with plasma membranes modifying permeability and can promote the release of viral particles. While these proteins are not essential for virus replication, their activity certainly promotes virus...

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PMID: 20300659
DOI: 10.1371/journal.ppat.1000801

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