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JC Polyomavirus Entry by Clathrin-Mediated Endocytosis Is Driven by β-Arrestin

29 Jan 2019

Abstract excerpt

Viruses usurp cellular factors to invade host cells. Activation and utilization of these proteins upon initiation of viral infection are therefore required for productive infection and resultant viral disease. The majority of healthy individuals are asymptomatically infected by JC polyomavirus (JCPyV), but if the host immune system is compromised, JCPyV can cause progressive multifocal leukoencephalopathy (PML),...

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PMID: 30700597
DOI: 10.1128/jvi.01948-18

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